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Knowing How the Brain Reacts to Smells May Help Fight Disease

May 11, 2022

From WebMD

You know that complicated equations can predict what story pops up in your news feed or which TikTok video you’ll watch next. But you might not know that math can help us understand what happens in the brain when we smell something.

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester are building complex mathematical models that do just that – and if they continue to make progress, their work may aid in the fight against diseases of the nervous system, like Alzheimer’s and Parkinson’s.

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Diverse minds and determined hearts make change: Forging equitability in Neuroscience

April 25, 2022

A group, mostly consisting of neuroscientists, meets bi-weekly outside the lab with a simple but powerful common purpose – to fundamentally change the bench.

"This experience has been eye-opening,” said Manuel Gomez-Ramirez, Ph.D., assistant professor of Brain and Cognitive Sciences at the University of Rochester and chair of the Del Monte Institute for Neuroscience Diversity Commission. “It is such a diverse group in every sense – cultural, gender, experience in both academics and nonacademics – we are all able to have input and listen to each other while considering different perspectives and focusing on one problem together."

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Student Spotlight: Victoria Popov

April 25, 2022

Victoria Popov is a second year in the Neuroscience Graduate Program at the University of Rochester Medical Center. Popov graduated from Rochester Institute of Technology with an M.S. in professional studies with concentrations in biomedical sciences, psychology, and health systems administration. She graduated with a B.S. from RIT in biomedical sciences.

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CVS graduate student Emily Isenstein receives pre-doctoral fellowship from Autism Science Foundation

April 19, 2022

The Autism Science Foundation (ASF), a nonprofit organization dedicated to funding innovative autism research and supporting families facing autism, today announced the recipients of its annual pre- and postdoctoral fellowship grants. BCS graduate student Emily Isenstein is among the recipients.

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The art of smell: Research suggests the brain processes smell both like a painting and a symphony

April 4, 2022

What happens when we smell a rose? How does our brain process the essence of its fragrance? Is it like a painting – a snapshot of the flickering activity of cells – captured in a moment in time? Or like a symphony, an evolving ensemble of different cells working together to capture the scent? New research suggests that our brain does both.

"These findings reveal a core principle of the nervous system, flexibility in the kinds of calculations the brain makes to represent aspects of the sensory world," said Krishnan Padmanabhan, Ph.D., an associate professor of Neuroscience and senior author of the study recently published in Cell Reports. "Our work provides scientists with new tools to quantify and interpret the patterns of activity of the brain."

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Congratulations to the Poster Abstract Winners at the 2022 CVS Retreat

March 31, 2022

Thanks to generous donations from the Rochester chapter of Society for Neuroscience and two anonymous donors, CVS was able to award a total of $950 in prize money for the poster competition at the CVS Retreat on March 25, 2022.

Howard Li profile

1st place ($350): Howard Li (Rucci lab), Saccade-amplitude dependent enhancement of visual sensitivity

Boris Penaloza profile

2nd place ($250): Boris Penaloza (DeAngelis/Haefner labs), Divisive normalization as a mechanism for hierarchical causal inference in motion perception

Katherine Andersh profile

3rd place ($150): Katherine Andersh (Libby lab), The role of proinflammatory cytokines in retinal ganglion cell death

Honorary Mentions ($50 each):

Yongyi (Christie) Cai profile

Yongyi (Christie) Cai (Williams lab), Image scanning microscopy for in vivo ganglion cells classification

Samantha Jenks profile

Samantha Jenks (Poletti lab), Visual anisotropies within the foveola

Ben Moon profile

Ben Moon (Rolland lab), Alignment and validation of an AOSLO for imaging the human cone mosaic in the central fovea

Zoe Stearns profile

Zoe Stearns (Poletti lab), Temporal dynamics of peri-microsaccadic perceptual modulations in the foveola


A key to restoring sight may be held in a drug that treats alcoholism

March 18, 2022

Researchers may have found a way to revive some vision loss caused by age-related macular degeneration – the leading cause of blindness – and the inherited disease retinitis pigmentosa (RP), a rare genetic disorder that causes the breakdown and loss of cells in the retina. The drug disulfiram – marketed under the brand name Antabuse – used to treat alcoholism, may hold the key to restoring this vision loss.

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Researchers restore brain immune system function after prenatal exposure to environmental toxin

February 11, 2022

From Medical Xpress

New research shows that exposure to the industrial byproduct TCDD in utero could cause the brain's immune system to go array later in life, damaging important brain circuits, and potentially giving rise to neurodevelopmental disorders, such as autism and ADHD. TCDD is primarily released into the environment by vehicle exhaust and burning wood and low levels of the toxin are found in air, soil, and food. The most common way people are exposed is through meat, dairy, and fish.

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International vision association honors Susana Marcos

February 4, 2022

Susana Marcos, the David R. Williams Director of the Center for Visual Science at the University of Rochester, has been elected to the 2022 class of Gold Fellows by the Association for Research in Vision and Ophthalmology (ARVO). The largest eye and vision research organization has a membership of nearly 11,000 researchers from more than 75 countries.

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Researchers provide insight into how the brain multitasks while walking

January 24, 2022

New research turns the old idiom about not being able to walk and chew gum on its head. Scientists with the Del Monte Institute for Neuroscience at the University of Rochester have shown that the healthy brain is able to multitask while walking without sacrificing how either activity is accomplished.

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Student Spotlight: Bryan Redmond

January 24, 2022

Bryan Redmond is a second year in the Neuroscience Graduate Program, and fourth year in the Medical Scientist Training Program at the University of Rochester School of Medicine and Dentistry. Redmond graduated from Xavier University of Louisiana with a B.S. in psychology.

Redmond’s research interest lies in the visual deficits experienced following optical lobe stroke. He is currently working in the lab of Krystel Huxlin, Ph.D., investigating whether neurons in undamaged areas of the visual circuit can be stimulated to restore vision following stroke. “There are no gold standard therapies for helping these patients recover their vision,” Redmond said. “If you have a motor stroke, you go to rehab, and keep training a muscle until you regain function. Patients with visual stroke are taught compensatory eye movements to make up for the blind field segment, or they are prescribed glasses with special lenses. These options teach patients to cope with their deficiency. We hope to develop a way to help them recover.”

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How we recognize one voice in a noisy crowd

January 11, 2022

From The Optimist Daily

Whether we’re at a busy restaurant, birthday party, or on public transport, sometimes our brain needs to focus on a single speaker amongst a multitude of background noise. A group of scientists from the University of Rochester Medical Center, wanted to see exactly how our incredible organ processes these stimuli.

The research team, led by Edmund Lalor, Ph.D., looked at exactly how our brains focus on the information from one speaker, whilst blocking out the background. Willing participants were asked to listen to two stories being told at once, and hold their attention on only one. EEG brainwave recordings were taken to try and unlock the neuronal activity occurring.

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